Amar Chitra Katha - The Rainbow Prince: Two Folk Tales from by Anant Pai

By Anant Pai

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Crystals observed in urine may form de novo during transport to the laboratory or during storage at room or refrigerator temperature. Crystals present in urine at the time of the collection may increase in number and size during storage at room temperature. Refrigeration increases the precipitation of all types of crystals. (1) Crystals formed during storage and cooling of the sample before analysis do not readily go back into solution when the sample is re-warmed. (2) Crystals that form after collection of the urine sample are of no clinical relevance for urolith or urethral plug formation.

5) Cystatin C determinations are not routinely available from commercial diagnostic ­laboratories. The renal clearance of a substance is that volume of plasma that would have to be filtered by the glomeruli each minute to account for the amount of that substance appearing in the urine each minute. The renal clearance of a substance (x) that is neither reabsorbed nor secreted by the tubules is equal to the GFR. Thus, GFR = UxV/Px. Creatinine is produced endogenously and excreted by glomerular filtration.

A) Production and excretion increase after a high protein meal. A BUN concentration of 30 to 40 mg/dL may occur 4 to 8 hours after feeding a high-protein meal in dogs. Therefore, an 8- to 12-hour fast is recommended before measurement. (b) Gastrointestinal bleeding can increase BUN concentration because blood represents an endogenous protein load. , starvation, infection, fever) also can increase BUN concentration. , tetracyclines) but these effects are minimal. (e) BUN concentration can be decreased by low-protein diets, anabolic steroids, severe hepatic insufficiency, or portosystemic shunting.

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